The osteoprotegerin/osteoprotegerin ligand family: role in inflammation and bone loss.
نویسنده
چکیده
منابع مشابه
Combined Hydroxyapatite Scaffold and Stem Cell from Human Exfoliated Deciduous Teeth Modulating Alveolar Bone Regeneration via Regulating Receptor Activator of Nuclear Factor-Κb and Osteoprotegerin System
Background: Tissue engineering using Stem cell from Human Exfoliated Deciduous Teeth (SHED) and a natural biomaterials biomaterial scaffold has become a promising therapy for the alveolar bone defect. The aim of this study was to analyze the Osteoprotegerin (OPG) and Receptor Activator of NF-Κb ligand (RANKL) expression after the application of Hydroxyapatite scaffold and SHED.Methods: A labora...
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INTRODUCTION osteoprotegerin has emerged as a new candidate for the treatment of osteoporosis. However, high levels of osteoprotegerin have been linked to vascular calcification, an independent and well-defined risk factor for cardiovascular disease (CVD) and mortality. Thus, the action of osteoprotegerin in these situations has been questioned. OBJECTIVE to evaluate the effect of osteoproteg...
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Aims Activation of inflammatory processes is necessary immediately after myocardial infarction (MI), but if it continues excessively, it can facilitate the occurrence of MI. Considering the positive effects of exercise on inflammatory pathways and their reduction, it seems to play a crucial role in improving the condition of MI patients. Accordingly, the present study investigated the effect of...
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Bone erosion is a hallmark of rheumatoid arthritis. Recent evidence from experimental arthritis suggests that osteoclasts are essential for the formation of local bone erosions. Two essential regulators of osteoclastogenesis have recently been described: the receptor-activator of nuclear factor kappa B ligand, which promotes osteoclast maturation, and osteoprotegerin (OPG), which blocks osteocl...
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ورودعنوان ژورنال:
- The Journal of rheumatology
دوره 31 5 شماره
صفحات -
تاریخ انتشار 2004